HETEROPHANE PROTOTYPES WITH AZOLIUM OR AZOLE ANION BINDING MOTIFS
Ermitas Alcald, Neus Mesquida, Immaculada Dinarès and Anna Ibáñez
Pharmacology and Therapeutic Chemistry, Universitat de Barcelona, Spain
Abstract:
The number of fundamental roles played by anions in biological and chemical processes has resulted
in a demand for anionic synthetic receptors of great interest in the fields of anion transport, extraction
and sensing.Quaternary azolium salts and azoles have gained a place among the anion-binding
functional groups and have emerged as attractive starting points for the design of a variety of host
systems, from synthetic anion receptors and sensors to transporters.1-4 Continuing our research on
heterophane prototypes for processes controlled by hydrogen bonding networks, we focused our
attention on the following models: the bis(imidazolio)phane 1.2A, the bis(1,2,3-triazolo)phane 2 and the bis(1,2,3-
triazolium) counterpart 3.2A and report their binding properties.
